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Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis

BACKGROUND: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in...

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Библиографические подробности
Главные авторы: Kverka, Miloslav, Rossmann, Pavel, Tlaskalova-Hogenova, Helena, Klimesova, Klara, Jharap, Bindia, de Boer, Nanne K, Vos, Rene M, van Bodegraven, Adriaan A, Lukas, Milan, Mulder, Chris J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097145/
https://ncbi.nlm.nih.gov/pubmed/21545711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-47
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