Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis

BACKGROUND: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in...

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Main Authors: Kverka, Miloslav, Rossmann, Pavel, Tlaskalova-Hogenova, Helena, Klimesova, Klara, Jharap, Bindia, de Boer, Nanne K, Vos, Rene M, van Bodegraven, Adriaan A, Lukas, Milan, Mulder, Chris J
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097145/
https://ncbi.nlm.nih.gov/pubmed/21545711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-47
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