Altered gut microbiota promotes colitis-associated cancer in IL-1 receptor-associated kinase M deficient mice

BACKGROUND: Microbial sensing by Toll-like receptors (TLR) and its negative regulation have important role in the pathogenesis of inflammation-related cancer. In this study, we investigated the role of negative regulation of TLR signaling and gut microbiota in the development of colitis-associated c...

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Autors principals: Klimesova, Klara, Kverka, Miloslav, Zakostelska, Zuzana, Hudcovic, Tomas, Hrncir, Tomas, Stepankova, Renata, Rossmann, Pavel, Ridl, Jakub, Kostovcik, Martin, Mrazek, Jakub, Kopecny, Jan, Kobayashi, Koichi S., Tlaskalova-Hogenova, Helena
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744230/
https://ncbi.nlm.nih.gov/pubmed/23567778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e318281330a
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