Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis

BACKGROUND: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in...

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主要な著者: Kverka, Miloslav, Rossmann, Pavel, Tlaskalova-Hogenova, Helena, Klimesova, Klara, Jharap, Bindia, de Boer, Nanne K, Vos, Rene M, van Bodegraven, Adriaan A, Lukas, Milan, Mulder, Chris J
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097145/
https://ncbi.nlm.nih.gov/pubmed/21545711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-47
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