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NO-released Zinc Supports the Simultaneous Binding of Raf-1 and PKCγ Cysteine-Rich Domains to HINT1 Protein at the Mu-Opioid Receptor
In the brain, the mu-opioid receptor (MOR) activates neural nitric oxide synthase (nNOS) through the PI3K/Akt pathway. The resulting nitric oxide (NO) enhances the function of the glutamate N-methyl-d-aspartate receptor (NMDAR)/calcium and calmodulin-dependent serine/threonine kinase (CaMKII), which...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096893/ https://ncbi.nlm.nih.gov/pubmed/21235400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3511 |
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