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NO-released Zinc Supports the Simultaneous Binding of Raf-1 and PKCγ Cysteine-Rich Domains to HINT1 Protein at the Mu-Opioid Receptor

In the brain, the mu-opioid receptor (MOR) activates neural nitric oxide synthase (nNOS) through the PI3K/Akt pathway. The resulting nitric oxide (NO) enhances the function of the glutamate N-methyl-d-aspartate receptor (NMDAR)/calcium and calmodulin-dependent serine/threonine kinase (CaMKII), which...

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Detalhes bibliográficos
Main Authors: Rodríguez-Muñoz, María, de la Torre-Madrid, Elena, Sánchez-Blázquez, Pilar, Garzón, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096893/
https://ncbi.nlm.nih.gov/pubmed/21235400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3511
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