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Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteins.
A 34-mer oligonucleotide containing a single 7,8-dihydro-8-oxoguanine (8-OxoG) residue was used to study the enzymatic and DNA binding properties of the Fpg protein from E. coli. The highest rates of incision of the 8-OxoG containing strand by the Fpg protein were observed for duplexes where 8-OxoG...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309678/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8332499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.12.2899 |
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