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DNA containing a chemically reduced apurinic site is a high affinity ligand for the E. coli formamidopyrimidine-DNA glycosylase.

The E. coli Formamidopyrimidine-DNA Glycosylase (FPG protein), a monomeric DNA repair enzyme of 30.2 kDa, was purified to homogeneity in large quantities. The FPG protein excises imidazole ring-opened purines and 8-hydroxyguanine residues from DNA. Besides DNA glycosylase activity, the FPG protein i...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Castaing, B, Boiteux, S, Zelwer, C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1992
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741272/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.3.389
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