MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

Mutations in MECP2, encoding methyl CpG binding protein 2, cause the neurodevelopmental disorder Rett syndrome. MeCP2 is an abundant nuclear protein that binds to chromatin and modulates transcription in response to neuronal activity. Prior studies of MeCP2 function have focused on specific gene tar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Singleton, Malaika K., Gonzales, Michael L., Leung, Karen N., Yasui, Dag H., Schroeder, Diane I., Dunaway, Keith, LaSalle, Janine M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096744/
https://ncbi.nlm.nih.gov/pubmed/21420494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.03.011
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