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MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation
Mutations in MECP2, encoding methyl CpG binding protein 2, cause the neurodevelopmental disorder Rett syndrome. MeCP2 is an abundant nuclear protein that binds to chromatin and modulates transcription in response to neuronal activity. Prior studies of MeCP2 function have focused on specific gene tar...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096744/ https://ncbi.nlm.nih.gov/pubmed/21420494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.03.011 |
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