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Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells?

Hepatitis B virus (HBV) is a major etiologic agent of chronic liver disease (CLD) and hepatocellular carcinoma (HCC). HBV encoded X antigen, HBx, and pathways implicated in the self-renewal of stem cells contribute to HCC, but it is not clear whether HBx expression promotes “stemness.” Thus, experim...

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Detalhes bibliográficos
Main Authors: Arzumanyan, Alla, Friedman, Tiffany, Ng, Irene O. L., Clayton, Marcia M., Lian, Zhaorui, Feitelson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096741/
https://ncbi.nlm.nih.gov/pubmed/21464043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3951
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