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Epigenetic repression of E-cadherin expression by Hepatitis B virus x Antigen (HBx) in liver cancer
Loss of E-cadherin is associated with acquisition of metastatic capacity. Numerous studies suggest histone deacetylation and/or hypermethylation of CpG islands in E-cadherin gene (CDH1) are major mechanisms responsible for E-cadherin silencing in different tumors and cancer cell lines. The Hepatitis...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183380/ https://ncbi.nlm.nih.gov/pubmed/21706058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.255 |
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