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Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes.

Interferon regulatory factor 1 (IRF-1) is a DNA-binding factor which recognizes regulatory elements in the promoters of interferon (IFN)-beta and some IFN-inducible genes. We observed that expression of transfected murine IRF-1 in different mammalian cell lines leads to down-regulation or stop of pr...

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Autori principali: Kirchhoff, S, Schaper, F, Hauser, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC309674/
https://ncbi.nlm.nih.gov/pubmed/8332497
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