Mutation of a Conserved Hydrophobic Patch Prevents Incorporation of ZP3 into the Zona Pellucida Surrounding Mouse Eggs

Three glycoproteins (ZP1, ZP2, and ZP3) are synthesized in growing mouse oocytes and secreted to form an extracellular zona pellucida that mediates sperm binding and fertilization. Each has a signal peptide to direct it into a secretory pathway, a “zona” domain implicated in matrix polymerization an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhao, Ming, Gold, Lyn, Dorward, Heidi, Liang, Li-fang, Hoodbhoy, Tanya, Boja, Emily, M. Fales, Henry, Dean, Jurrien
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Cell Growth and Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC309620/
https://ncbi.nlm.nih.gov/pubmed/14645511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.8982-8991.2003
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