Interaction between FLASH and Lsm11 is essential for histone pre-mRNA processing in vivo in Drosophila

Metazoan replication-dependent histone mRNAs are the only nonpolyadenylated cellular mRNAs. Formation of the histone mRNA 3′ end requires the U7 snRNP, which contains Lsm10 and Lsm11, and FLASH, a processing factor that binds Lsm11. Here, we identify sequences in Drosophila FLASH (dFLASH) that bind...

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Hauptverfasser: Burch, Brandon D., Godfrey, Ashley C., Gasdaska, Pamela Y., Salzler, Harmony R., Duronio, Robert J., Marzluff, William F., Dominski, Zbigniew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096045/
https://ncbi.nlm.nih.gov/pubmed/21525146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2566811
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