The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing

Unlike canonical pre-mRNAs, animal replication-dependent histone pre-mRNAs lack introns and are processed at the 3’-end by a mechanism distinct from cleavage and polyadenylation. They have a 3’ stem loop and histone downstream element (HDE) that are recognized by stem-loop binding protein (SLBP) and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Aik, Wei Shen, Lin, Min-Han, Tan, Dazhi, Tripathy, Ashutosh, Marzluff, William F., Dominski, Zbigniew, Chou, Chi-Yuan, Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636114/
https://ncbi.nlm.nih.gov/pubmed/29020104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186034
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