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Activation of picornaviral IRESs by PTB shows differential dependence on each PTB RNA-binding domain
Polypyrimidine tract binding protein (PTB) is an RNA-binding protein with four RNA-binding domains (RBDs). It is a major regulator of alternative splicing and also stimulates translation initiation at picornavirus IRESs (internal ribosome entry sites). The sites of interaction of each RBD with two p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096044/ https://ncbi.nlm.nih.gov/pubmed/21518806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2549411 |
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