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Understanding the molecular basis of substrate binding specificity of PTB domains

Protein-protein interactions mediated by phosphotyrosine binding (PTB) domains play a crucial role in various cellular processes. In order to understand the structural basis of substrate recognition by PTB domains, multiple explicit solvent atomistic simulations of 100ns duration have been carried o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Sain, Neetu, Tiwari, Garima, Mohanty, Debasisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985636/
https://ncbi.nlm.nih.gov/pubmed/27526776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31418
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