Polypyrimidine Tract-binding Protein (PTB) Differentially Affects Malignancy in a Cell Line-dependent Manner

RNA processing is altered during malignant transformation, and expression of the polypyrimidine tract-binding protein (PTB) is often increased in cancer cells. Although some data support that PTB promotes cancer, the functional contribution of PTB to the malignant phenotype remains to be clarified....

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Autores principales: Wang, Chen, Norton, John T., Ghosh, Supurna, Kim, Julie, Fushimi, Kazuo, Wu, Jane Y., Stack, M. Sharon, Huang, Sui
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
RNA: Processing and Catalysis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459264/
https://ncbi.nlm.nih.gov/pubmed/18499661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803682200
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