Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis

PAI-1 has been shown to be both profibrotic and antifibrotic in animal models of hepatic fibrosis. Although these models have similarities to human fibrotic liver disease, no rodent model completely recapitulates the clinical situation; indeed, transaminase values in most models of hepatic fibrosis...

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Hlavní autoři: Beier, Juliane I., Kaiser, J Phillip, Guo, Luping, Martínez-Maldonado, Manuel, Arteel, Gavin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095665/
https://ncbi.nlm.nih.gov/pubmed/21501583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.04.001
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