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PKCε contributes to chronic ethanol-induced steatosis in mice but not inflammation and necrosis

BACKGROUND/AIMS: Protein kinase c-epsilon (PKCε) has been shown to play a role in experimental steatosis by acute alcohol. The 'two-hit' hypothesis implies that preventing steatosis should blunt more advanced liver damage (e.g., inflammation and necrosis). However, the role of PKCε in thes...

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Autores principales: Kaiser, J. Phillip, Guo, Luping, Beier, Juliane I., Zhang, Jun, Bhatnagar, Aruni, Arteel, Gavin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157371/
https://ncbi.nlm.nih.gov/pubmed/24483773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12324
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