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PKCε contributes to chronic ethanol-induced steatosis in mice but not inflammation and necrosis
BACKGROUND/AIMS: Protein kinase c-epsilon (PKCε) has been shown to play a role in experimental steatosis by acute alcohol. The 'two-hit' hypothesis implies that preventing steatosis should blunt more advanced liver damage (e.g., inflammation and necrosis). However, the role of PKCε in thes...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157371/ https://ncbi.nlm.nih.gov/pubmed/24483773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12324 |
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