Metformin Prevents Alcohol-Induced Liver Injury in the Mouse: Critical Role of Plasminogen Activator Inhibitor-1

BACKGROUND & AIMS: The biguanide drug metformin has recently been found to improve steatosis and liver damage in animal models and in humans with non-alcoholic steatohepatitis. METHODS: The aim of the present study was to determine whether metformin also prevents steatosis and liver damage in mo...

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Hlavní autoři: BERGHEIM, INA, GUO, LUPING, DAVIS, MOLLY ANNE, LAMBERT, JASON C., BEIER, JULIANE I., DUVEAU, ILINCA, LUYENDYK, JAMES P., ROTH, ROBERT A., ARTEEL, GAVIN E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648856/
https://ncbi.nlm.nih.gov/pubmed/16762632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2006.03.020
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