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The core of Ure2p prion fibrils is formed by the N-terminal segment in a parallel cross-β structure: Evidence from solid state NMR
Intracellular fibril formation by Ure2p produces the non-Mendelian genetic element [URE3] in S. cerevisiae, making Ure2p a prion protein. We show that solid state NMR spectra of full-length Ure2p fibrils, seeded with infectious prions from a specific [URE3] strain and labeled with uniformly (15)N,(1...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095661/ https://ncbi.nlm.nih.gov/pubmed/21497604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.067 |
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