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Curing of the [URE3] prion by Btn2p, a Batten disease-related protein
[URE3] is a prion (infectious protein), a self-propagating amyloid form of Ure2p, a regulator of yeast nitrogen catabolism. We find that overproduction of Btn2p, or its homologue Ypr158 (Cur1p), cures [URE3]. Btn2p is reported to be associated with late endosomes and to affect sorting of several pro...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572181/ https://ncbi.nlm.nih.gov/pubmed/18833194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.198 |
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