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Normal levels of the antiprion proteins Btn2 and Cur1 cure most newly formed [URE3] prion variants
[URE3] is an amyloid prion of the Saccharomyces cerevisiae Ure2p, a regulator of nitrogen catabolism. Overproduction of Btn2p, involved in late endosome to Golgi protein transport, or its paralog Cur1p, cures [URE3]. Btn2p, in curing, is colocalized with Ure2p in a single locus, suggesting sequestra...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084489/ https://ncbi.nlm.nih.gov/pubmed/24938787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409582111 |
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