Identification of Methylated Genes Associated with Aggressive Clinicopathological Features in Mantle Cell Lymphoma

BACKGROUND: Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) translocation and a high number of secondary chromosomal alterations. The contribution of DNA methylation to MCL lymphomagenesis is not well known. We sought to identify epigenetically silenced genes in thes...

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Détails bibliographiques
Auteurs principaux: Enjuanes, Anna, Fernàndez, Verònica, Hernández, Luis, Navarro, Alba, Beà, Sílvia, Pinyol, Magda, López-Guillermo, Armando, Rosenwald, Andreas, Ott, German, Campo, Elías, Jares, Pedro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095614/
https://ncbi.nlm.nih.gov/pubmed/21603610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019736
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