Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling

Mantle cell lymphoma (MCL) is genetically characterized by the t(11;14)(q13;q32) translocation and a high number of secondary chromosomal alterations. However, only a limited number of target genes have been identified. We have studied 10 MCL cell lines and 28 primary tumors with a combination of a...

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Detalhes bibliográficos
Main Authors: Beà, Sílvia, Salaverria, Itziar, Armengol, Lluís, Pinyol, Magda, Fernández, Verónica, Hartmann, Elena M., Jares, Pedro, Amador, Virginia, Hernández, Luís, Navarro, Alba, Ott, German, Rosenwald, Andreas, Estivill, Xavier, Campo, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662646/
https://ncbi.nlm.nih.gov/pubmed/18984860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170183
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