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Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

Acquired homozygosity in the form of segmental acquired uniparental disomy (aUPD) has been described in follicular lymphoma (FL) and is usually due to mitotic recombination. SNP array analysis was performed with the use of the Affymetrix 10K 2.0 Gene-chip array on DNA from 185 diagnostic FL patients...

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Autors principals: O'Shea, Derville, O'Riain, Ciarán, Gupta, Manu, Waters, Rachel, Yang, Youwen, Wrench, David, Gribben, John, Rosenwald, Andreas, Ott, German, Rimsza, Lisa M., Holte, Harald, Cazier, Jean-Baptiste, Johnson, Nathalie A., Campo, Elias, Chan, Wing C., Gascoyne, Randy D., Young, Bryan D., Staudt, Louis M., Lister, T. Andrew, Fitzgibbon, Jude
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652373/
https://ncbi.nlm.nih.gov/pubmed/19141865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174953
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