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Naturally Occurring Osmolyte, Trehalose Induces Functional Conformation in an Intrinsically Disordered Activation Domain of Glucocorticoid Receptor

Intrinsically disordered (ID) regions are frequently found in the activation domains of many transcription factors including nuclear hormone receptors. It is believed that these ID regions promote molecular recognition by creating large surfaces suitable for interactions with their specific protein...

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Bibliografiske detaljer
Main Authors: Khan, Shagufta H., Arnott, John A., Kumar, Raj
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095608/
https://ncbi.nlm.nih.gov/pubmed/21603604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019689
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