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Naturally Occurring Osmolyte, Trehalose Induces Functional Conformation in an Intrinsically Disordered Activation Domain of Glucocorticoid Receptor

Intrinsically disordered (ID) regions are frequently found in the activation domains of many transcription factors including nuclear hormone receptors. It is believed that these ID regions promote molecular recognition by creating large surfaces suitable for interactions with their specific protein...

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Detalhes bibliográficos
Main Authors: Khan, Shagufta H., Arnott, John A., Kumar, Raj
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095608/
https://ncbi.nlm.nih.gov/pubmed/21603604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019689
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