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Naturally Occurring Osmolyte, Trehalose Induces Functional Conformation in an Intrinsically Disordered Activation Domain of Glucocorticoid Receptor

Intrinsically disordered (ID) regions are frequently found in the activation domains of many transcription factors including nuclear hormone receptors. It is believed that these ID regions promote molecular recognition by creating large surfaces suitable for interactions with their specific protein...

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Hlavní autoři: Khan, Shagufta H., Arnott, John A., Kumar, Raj
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095608/
https://ncbi.nlm.nih.gov/pubmed/21603604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019689
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