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Structure-based Design of a Heptavalent Anthrax Toxin Inhibitor
The design of polyvalent molecules, consisting of multiple copies of a biospecific ligand attached to a suitable scaffold, represents a promising approach to inhibit pathogens and oligomeric microbial toxins. Despite the increasing interest in structure-based drug design, few polyvalent inhibitors b...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095510/ https://ncbi.nlm.nih.gov/pubmed/21302959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm101396u |
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