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Synthesis of Potent Inhibitors of Anthrax Toxin Based on Poly-L-Glutamic Acid
We report the synthesis of biodegradable polyvalent inhibitors of anthrax toxin based on poly-L-glutamic acid (PLGA). These biocompatible polyvalent inhibitors are at least four orders of magnitude more potent than the corresponding monovalent peptides in vitro and are comparable in potency to polya...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698798/ https://ncbi.nlm.nih.gov/pubmed/16984137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060042y |
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