Design of Monodisperse and Well-defined Polypeptide-based Polyvalent Inhibitors of Anthrax Toxin(;)

The design of polyvalent molecules, presenting multiple copies of a specific ligand, represents a promising strategy to inhibit pathogens and toxins. The ability to control independently the valency and the spacing between ligands would be valuable for elucidating structure-activity relationships an...

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Main Authors: Patke, Sanket, Boggara, Mohan, Maheshwari, Ronak, Srivastava, Sunit K., Arha, Manish, Douaisi, Marc, Martin, Jacob T., Harvey, Ian B., Brier, Matthew, Rosen, Tania, Mogridge, Jeremy, Kane, Ravi S.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116455/
https://ncbi.nlm.nih.gov/pubmed/24706570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201400870
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