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Exploiting the homologous recombination DNA repair network for targeted cancer therapy
Genomic instability is a characteristic of cancer cells. In order to maintain genomic integrity, cells have evolved a complex DNA repair system to detect, signal and repair a diversity of DNA lesions. Homologous recombination (HR)-mediated DNA repair represents an error-free repair mechanism to main...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Baishideng Publishing Group Co., Limited
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095467/ https://ncbi.nlm.nih.gov/pubmed/21603316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v2.i2.73 |
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