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Domains of the Rsp5 Ubiquitin-Protein Ligase Required for Receptor-mediated and Fluid-Phase Endocytosis

Yeast Rsp5p and its mammalian homologue, Nedd4, are hect domain ubiquitin-protein ligases (E3s) required for the ubiquitin-dependent endocytosis of plasma membrane proteins. Because ubiquitination is sufficient to induce internalization, E3-mediated ubiquitination is a key regulatory event in plasma...

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Main Authors: Dunn, Rebecca, Hicke, Linda
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC30953/
https://ncbi.nlm.nih.gov/pubmed/11179425
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