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Opposite effects of endogenous peptide/class I MHC on T cell activity in the presence and absence of CD8

Non-stimulatory or endogenous pepMHC presented on the surface of APCs, either alone or alongside agonist pepMHC, play various roles in T cell selection and activation. To examine these properties in more detail, here we explored several model systems of TCR and pepMHC ligands with sufficient affinit...

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Hlavní autoři: Stone, Jennifer D., Aggen, David H., Chervin, Adam S., Narayanan, Samanthi, Schmitt, Thomas M., Greenberg, Philip D., Kranz., David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095212/
https://ncbi.nlm.nih.gov/pubmed/21451107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003755
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