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Opposite effects of endogenous peptide/class I MHC on T cell activity in the presence and absence of CD8
Non-stimulatory or endogenous pepMHC presented on the surface of APCs, either alone or alongside agonist pepMHC, play various roles in T cell selection and activation. To examine these properties in more detail, here we explored several model systems of TCR and pepMHC ligands with sufficient affinit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095212/ https://ncbi.nlm.nih.gov/pubmed/21451107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003755 |
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