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Anergic Responses Characterize a Large Fraction of Human Autoreactive Naïve B Cells Expressing Low Levels of Surface IgM
B cell anergy represents an important mechanism of peripheral immunological tolerance for mature autoreactive B cells that escape central tolerance enforced by receptor editing and clonal deletion. While well documented in mice, the extent of its participation in human B cell tolerance remains to be...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095097/ https://ncbi.nlm.nih.gov/pubmed/21398610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001946 |
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