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Combination therapies for lysosomal storage disease: is the whole greater than the sum of its parts?

Lysosomal storage diseases (LSDs), as a group, are among the most common inherited diseases affecting children. The primary defect is typically a genetic deficiency of one of the lysosomal enzymes, often causing accumulation of undegraded substrates within the lysosome. This accumulation causes nume...

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Bibliografische gegevens
Hoofdauteurs: Hawkins-Salsbury, Jacqueline A., Reddy, Adarsh S., Sands, Mark S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095053/
https://ncbi.nlm.nih.gov/pubmed/21421999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr112
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