RSK2 Binding Models Delineate Key Features for Activity

Due to its overexpression and activation in human cancer cells and tissues, an emerging molecular target in cancer therapeutics is p90 ribosomal s6 kinase 2 (RSK2). While a growing number of RSK2 inhibitors have been reported in the literature, only the crystal structure of RSK2 in complex with an A...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gussio, Rick, Currens, Michael J., Scudiero, Dominic A., Smith, Jeffrey A., Lannigan, Deborah A., Shoemaker, Robert H., Zaharevitz, Dan W., Nguyen, Tam Luong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094916/
https://ncbi.nlm.nih.gov/pubmed/21593990
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