Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer

The pathogenesis of breast cancer involves multiple genetic and epigenetic events. In this study, we report an epigenetic alteration of DFNA5 in human breast cancer. DFNA5 gene was silenced in breast cancer cell lines that were methylated in the DFNA5 promoter, and restored by treatment with the dem...

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Detalhes bibliográficos
Main Authors: Kim, Myoung Sook, Lebron, Cinthia, Nagpal, Jatin K., Chae, Young Kwang, Chang, Xiaofei, Huang, Yiping, Chuang, Tony, Yamashita, Keishi, Trink, Barry, Ratovitski, Edward A., Califano, Joseph A., Sidransky, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094717/
https://ncbi.nlm.nih.gov/pubmed/18346456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.026
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