Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers

The human cysteine dioxygenase 1 (CDO1) gene is a non-heme structured, iron-containing metalloenzyme involved in the conversion of cysteine to cysteine sulfinate, and plays a key role in taurine biosynthesis. In our search for novel methylated gene promoters, we have analyzed differential RNA expres...

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Detalhes bibliográficos
Main Authors: Brait, Mariana, Ling, Shizhang, Nagpal, Jatin K., Chang, Xiaofei, Park, Hannah Lui, Lee, Juna, Okamura, Jun, Yamashita, Keishi, Sidransky, David, Kim, Myoung Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459978/
https://ncbi.nlm.nih.gov/pubmed/23028699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044951
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