Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers

The human cysteine dioxygenase 1 (CDO1) gene is a non-heme structured, iron-containing metalloenzyme involved in the conversion of cysteine to cysteine sulfinate, and plays a key role in taurine biosynthesis. In our search for novel methylated gene promoters, we have analyzed differential RNA expres...

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Détails bibliographiques
Auteurs principaux: Brait, Mariana, Ling, Shizhang, Nagpal, Jatin K., Chang, Xiaofei, Park, Hannah Lui, Lee, Juna, Okamura, Jun, Yamashita, Keishi, Sidransky, David, Kim, Myoung Sook
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459978/
https://ncbi.nlm.nih.gov/pubmed/23028699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044951
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