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Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning

PURPOSE: To calculate the Linear Energy Transfer (LET) distributions in patients undergoing proton therapy. These distributions can be used to identify areas of elevated or diminished biological effect. The location of such areas might be influenced in intensity-modulated proton therapy (IMPT) optim...

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Autori principali: Grassberger, Clemens, Trofimov, Alexei, Lomax, Anthony, Paganetti, Harald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094592/
https://ncbi.nlm.nih.gov/pubmed/21163588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.10.027
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