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Development of an MHC class I L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8(+) T cells in the mouse
OBJECTIVES: We set out to develop a prostate specific antigen (PSA) peptide-loaded tetramer for enumeration of PSA-specific CD8(+) T cells in the Balb/c mouse model. METHODS: A candidate MHC class I PSA peptide (HPQKVTKFML(188–197)) was selected based on its ability to restimulate PSA-specific CD8(+...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094480/ https://ncbi.nlm.nih.gov/pubmed/21263453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pcan.2010.57 |
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