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Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres

BACKGROUND: Breast cancer is one of the most prevalent cancers in the world and more than one million women are diagnosed leading to 410,000 deaths every year. In our previous studies new chalcone-imidazolone conjugates were prepared and evaluated for their anticancer activity in a panel of 53 human...

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Detalhes bibliográficos
Main Authors: Ramaiah, M Janaki, Pushpavalli, SNCVL, Krishna, G Rama, Sarma, Pranjal, Mukhopadhyay, Debasmita, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika Pal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094261/
https://ncbi.nlm.nih.gov/pubmed/21518433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-11
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