Integrin-mediated Adhesion Regulates Cell Polarity and Membrane Protrusion through the Rho Family of GTPases

Integrin-mediated adhesion is a critical regulator of cell migration. Here we demonstrate that integrin-mediated adhesion to high fibronectin concentrations induces a stop signal for cell migration by inhibiting cell polarization and protrusion. On fibronectin, the stop signal is generated through α...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Cox, Elisabeth A., Sastry, Sarita K., Huttenlocher, Anna
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179414/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.2.265
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