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Integrin-mediated Adhesion Regulates Cell Polarity and Membrane Protrusion through the Rho Family of GTPases

Integrin-mediated adhesion is a critical regulator of cell migration. Here we demonstrate that integrin-mediated adhesion to high fibronectin concentrations induces a stop signal for cell migration by inhibiting cell polarization and protrusion. On fibronectin, the stop signal is generated through α...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Cox, Elisabeth A., Sastry, Sarita K., Huttenlocher, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.2.265
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