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Integrin-mediated Adhesion Regulates Cell Polarity and Membrane Protrusion through the Rho Family of GTPases

Integrin-mediated adhesion is a critical regulator of cell migration. Here we demonstrate that integrin-mediated adhesion to high fibronectin concentrations induces a stop signal for cell migration by inhibiting cell polarization and protrusion. On fibronectin, the stop signal is generated through α...

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Détails bibliographiques
Auteurs principaux: Cox, Elisabeth A., Sastry, Sarita K., Huttenlocher, Anna
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC30942/
https://ncbi.nlm.nih.gov/pubmed/11179414
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