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Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release
Many anticancer drugs activate caspases via the mitochondrial apoptosis pathway. Activation of this pathway triggers a concomitant bioenergetic crisis caused by the release of cytochrome-c (cyt-c). Cancer cells are able to evade these processes by altering metabolic and caspase activation pathways....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094064/ https://ncbi.nlm.nih.gov/pubmed/21364572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.2 |
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