Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release

Many anticancer drugs activate caspases via the mitochondrial apoptosis pathway. Activation of this pathway triggers a concomitant bioenergetic crisis caused by the release of cytochrome-c (cyt-c). Cancer cells are able to evade these processes by altering metabolic and caspase activation pathways....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huber, Heinrich J, Dussmann, Heiko, Kilbride, Seán M, Rehm, Markus, Prehn, Jochen H M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094064/
https://ncbi.nlm.nih.gov/pubmed/21364572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.2
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